Anne Barker can't recognise any musical patterns at all, she has the musical equivalent of colour blindness, a condition called amusia. Yentob has an MRI scan while listening to different types of music to see how his brain activity alters. Next we meet Derek Paravicini, a young blind man with severe autism who is also a musical savante. Archive footage is shown from the documentary 'Awakenings' and he describes how the people he worked with who had sleepy sickness were brought back to life not just when given el dopa but also when hearing music. Sacks also talks about his own family and how important music was to them. Matt Giordano has severe Tourette's and uses drumming to ease his ticks. Alan Yentob goes to meet some of the people who feature in Sacks' work. Sacks' research has been into how people who have extraordinary medical conditions use music to help them. This documentary follows up on ideas put forward in Oliver Sacks' latest book 'Musicophilia'.
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